INSPIRE platform

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INSPIRE is an innovative research platform on geroscience & healthy aging gathering biological, clinical, digital and imaging data.

Main objectives of INSPIRE platform

Publié le 22/05/2020 à 12h30 (mis à jour le 22/05/2020 à 18h04)

This platform addresses 2 main objectives.

Objective 1 : identify hallmarks of biological aging

We have been using the notion of chronological age forever (or civil age, date of birth) but due to the increase of life expectancy and biological knowledge, this notion no longer reflects the real age of people. The current challenge is to determine biological age that will reflect people’s real age and that can have a global and pejorative impact on body functions.

Breakthroughs in biology lead to the new field of geroscience, and combined with the boost of artificial intelligence, they both allow researchers to work on biological age. Then when differences exist between biological age (including the intrinsic capacity study) and a person’s civil age (in correlation with the clinical evolution), physicians will propose targeted and customised actions. It will be particularly true for people with well-known hereditary factors such as a family history of Alzheimer Disease, macular degeneration, or cancer conditions).

Objective 2 : follow the evolution of the intrinsic capacity domains or functions

Intrinsic capacity is defined by 6 key functions: sensorial (vision, audition), mobility, cognitive (i.e memory), psychological and nutritional functions.

By locally implementing the WHO ICOPE Program (Integrated Care for Older People) for seniors 60 years old and over using the ICOPE mobile application, we will be able to follow the evolution of intrinsic capacity. WHO defines intrinsic capacity as the combination of the individual’s physical and mental, including psychological, capacities. Functional ability is the combination and interaction of intrinsic capacity with the environment a person inhabits.

This ICOPE program seeks to maintain senior people at their optimal level of capacities and to warn their general physician in the event of a functional decline in order to step in as early as possible to maintain their autonomy and prevent dependency.