Platform partners INSPIRE on gerosciences and healthy aging

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Founding members of INSPIRE platform

Publié le 22/05/2020 à 16h12

The project was initiated by the Gérontopôle du CHU de Toulouse in close collaboration with the Toulouse III - Paul Sabatier (UT3) University, the Institut National de la Santé et de la Recherche Médicale (Inserm), and the Centre National de la Recherche Scientifique (CNRS).

Teams involved since the creation of INSIPIRE
Team’s name Role and manager
Gérontopôle du CHU de Toulouse Prevention of Dependency during the course of aging : Assessment, prevention, treatment of declines (B. Vellas)
Laboratoire d’épidémiologie et analyses en santé publique (LEASP – INSERM / UT3) Methodology of clinical trials for the prevention of aging (S. Andrieu)
STROMALab (UMR 1031 Inserm / EFS / ENVT / UT3 et ERL CNRS) Mesenchymal and hematopoietic stem cells, regeneration and fibrosis (Louis Casteilla)
Centre de Physiopathologie Toulouse Purpan (CPTP – Inserm / CNRS / UT3) Neuroinflammation, biomarkers and responses to the challenges of immunology, inflammation and infectious diseases (R. Liblau)
Institut des Maladies Métaboliques et Cardiovasculaires (I2MC - UMR 1048 Inserm / UT3) The research activity developed at the Institute of Metabolic and Cardiovascular Diseases (I2MC) is centered on three main axes: the adipose tissue, obesity and diabetes axis, the thrombosis, atherosclerosis and vessels axis, the heart and kidney axis. (A. Parini)
Centre de Recherches sur la Cognition Animale (CRCA – CNRS / UT3) Understanding the mechanisms of memory (C. Rampon, Noélie Davezac)
Laboratoire Toulouse Neuro Imaging Center (ToNIC – Inserm / UT3) Precision medical imaging (P. Payoux)
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Funders of the INSPIRE plateform

Publié le 22/05/2020 à 16h28 (mis à jour le 22/05/2020 à 16h31)

The Occitania / Pyrénées-Méditerranée Region and Europe

This large-scale project is made possible by the significant support and financial commitment of :

For an initial period of three years, the Occitania Region mobilized a budget of €6.5 million in addition to the €6.3 million of the European ERDF Fund.

These two principal sources of funding enabled the creation of the INSPIRE platform, bringing together clinical, epidemiological, social, biological and digital resources for research and development.

In total, almost 57 million euros will be mobilized by the Region over 10 years as part of the INSPIRE project.

The Toulouse University Hospital, the University and research establishments

Apart from this regional funding, those of the CHU, the Toulouse III - Paul Sabatier University and the major research institutions (Inserm and CNRS) which fund the infrastructure, equipment and salaries of the permanent staff involved in INSPIRE platform.

Private partners

Finally, the platform received private co-funding for the creation of scientific chairs (Pfizer France, Pierre-Fabre Dermo-Cosmétique, Korian, Edenis and the APOC CTAD Foundation).

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Other academic partners of the INSPIRE platform

Publié le 22/05/2020 à 16h38 (mis à jour le 22/05/2020 à 16h41)

Academic partners of the INSPIRE platform
Partner’s name Role and manager
Digestive Health Research Institute (IRSD – Inserm / INRA / ENVT / UT3) Biomarkers of aging and fragility in the digestive system (N. Vergnolle)
University Department of General Medicine, Toulouse (DUMG – UT3) S. Oustric
The Clinique Universitaire du Sport of CHU Toulouse F. Pillard
The Federal Institute of Biology (IFB) of CHU Toulouse The Federal Institute of Biology (IFB) brings together the ten biology laboratories of Toulouse University Hospital, of which the Laboratory of Medical Biology (LBM) and transverse services including the multi-thematic Biological Resource Center Toulouse Bio Ressources (CRB TBR).
The medical biology laboratory (MBL) J. Izopet
Multi-thematic Biological Resource Center Toulouse Bio Ressources (CRB TBR) B. Perret
The Pharmacy Department of the Toulouse University Hospital P. Cestac
Epithelial Differentiation and Rheumatoid Autoimmunity Unit (UDEAR - Inserm / UT3) Molecular and cellular physiopathology of epithelia, autoimmunity and neuroimmune interactions (G. Serre)
The National Veterinary School of Toulouse I. Raymond-Letron
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Private partners on scientific chairs

Publié le 22/05/2020 à 16h47

Several private partners are involved in constituting human cohorts and funding scientific chairs of excellence for associated research between their company and CHU Toulouse, holder of the INSPIRE Platform for its Gérontopôle :

  • Pfizer France : study of the prevalence of pneumococcus in the INSPIRE population and its clinical implications for determining declines in the areas of intrinsic ability.
  • Pierre Fabre Dermo-Cosmétique : research on the biological aging of the skin (associations between the epidermal barrier and the immune system as well as the links between cutaneous, oral and intestinal dysbiosis). It will therefore be able to provide data on biomarkers of aging skin.
  • Korian : implementation of the WHO ICOPE program in the «Follow-up Care» unit, which will examine how the ICOPE program can facilitate care on a visit basis when a patient returns home.
  • Edenis : implementation of the WHO ICOPE program in Sheltered Housing and EHPAD which will determine how the ICOPE program can facilitate risk stratification and the prevention of functional decline and dependence in this population.
  • Fondation Alzheimer Preventia in Occitania / Catalonia (APOC) - Clinical Trials on Alzheimer’s Disease (CTAD) : study of innovative methodologies for future preventive clinical trials during the course of aging, focusing on cognitive decline and prevention of Alzheimer’s disease. The measurement of plasma β-amyloid signature as a predictive factor for decline and Alzheimer’s disease will be examined.
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Private partners (no scientific chairs)

Publié le 22/05/2020 à 16h53

The INSIPIRE platform is also supported by private partners outside scientific chairs :

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